αdbs Technology & System

Other DBS Systems are Guessing.
αDBS® Isn't.

For decades, DBS operated on a one-way signal — stimulating without listening. αDBS® changes that. Our patented closed-loop system reads the brain's own biomarkers and adapts in real time, creating a new standard for how neurological disease is treated.

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3000+

Biomarker values & 300 full LFP spectrum values

86%

Patient preference for αDBS

23%

Improvement over cDBS

50+

Patients treated

Product Portfolio

αDBS®: A Fully Integrated System,
From Implant to Cloud

Every component of the αDBS® system is designed to work together, continuously sensing, analyzing, adapting, and learning, to deliver precision neuromodulation at every moment of therapy.

Implantable Pulse Generator

αDBS IPG

Powered by a patented Adaptive Therapy Stim Engine, the αDBS IPG continuously senses full-spectrum local field potentials (LFPs) from any electrode, every 10 minutes, enabling real-time adaptation unmatched by any competing system. Rechargeable and upgradeable.

arrow_right Full-spectrum LFP sensing from any electrode

arrow_right Asymmetric sensing during active stimulation

arrow_right Rechargeable & upgradeable design

arrow_right Directional stimulation capability

Clinical Programming System

αDBS Clinical Programmer

An optimized clinician programming platform designed for both adaptive and conventional DBS. Provides real-time visualization of neural biomarkers, simplifies parameter adjustment, and reduces the time burden of patient programming sessions.

arrow_right Real-time LFP biomarker visualization

arrow_right Streamlined adaptive & conventional DBS programming

arrow_right Automated therapy optimization suggestions

Patient Remote

At-Home Device

Enables automatic data collection and wireless transmission from the patient's home. Captures continuous neural sensing data and therapy logs without requiring clinic visits — feeding the WebBioBank™ cloud platform with longitudinal, real-world data.

arrow_right Automatic background data upload

arrow_right Wireless transmission to WebBioBank™

arrow_right Remote patient status monitoring

Cloud Platform

WebBioBank™

Newronika's proprietary cloud data platform captures every moment of therapy in a longitudinal, structured data repository. With over 3000+ biomarker values and 300 full LFP spectrum values data collected per patient daily, WebBioBank™ powers biomarker discovery, population-level analysis, and AI-driven therapy optimization.

arrow_right Population-level trend analysis and AI insights

arrow_right New biomarker identification for future indications

Adaptive Technology

DBS That Responds. Not Just Delivers.

Conventional DBS delivers fixed stimulation to a brain that never stays the same. αDBS® closes the loop — continuously reading the brain’s signals and adjusting therapy in real time.

cDBS — Open Loop (Conventional)

Clinician Programs
‍Fixed stimulation parameters set at clinic visit

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IPG Delivers
‍Static, unchanging stimulation, only on or off.

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Patient Experiences
‍Symptom fluctuation, side effects, clinic dependency

↓

Clinic Visit Required
‍Manual reprogramming — weeks or months later

cDBS Limitations

✗ No neural feedback or sensing
✗ Cannot adapt to disease fluctuations
✗ Over- or under-stimulation common
✗ Frequent, costly clinic programming

αDBS® — Closed Loop (Adaptive)

Algorithm Analyzes & Adapts
‍Patented proportional control adjusts amplitude in real time

↓

IPG Senses Neural Biomarkers
‍Full-spectrum LFP recording, every 10 minutes, continuously

↓

Patient Experiences
Significantly reduced dyskinesia and other side effects

↓

Optimized Therapy Delivered
‍Right dose, right moment — no clinic visit needed

αDBS® Advantages

✓ Continuous real-time neural sensing
✓ Automatic, proportional therapy optimization
✓ Reduces over- and under-stimulation
✓ Remote data capture from home

Key Benefits of Closed-Loop Adaptive Therapy

Precision Therapy Delivered

Stimulation parameters update continuously based on real neural biomarkers — delivering the right dose at exactly the right moment, never more, never less.

Fewer Side Effects

By avoiding chronic overstimulation and understimulation, αDBS® significantly reduces dyskinesia and other stimulation-induced adverse events common with conventional DBS.

Continuous 24/7 Monitoring

Neural sensing every 10 minutes provides an unprecedented longitudinal picture of disease state — enabling biomarker discovery impossible with conventional systems.

Reduced Clinician Burden

Automated processes handle what previously required hands-on programming sessions — clinicians gain time, patients gain independence.

Remote Patient Management

Data uploads automatically from home, enabling clinicians to review neural trends and update therapy without requiring a clinic visit.

Population-Scale Learning

Every patient contributes to a growing neural dataset. WebBioBank™’s 9M+ minutes of data enables AI-driven biomarker identification for future indications.

WebBioBank™ PLATFORM

From Brain Signal to Clinical Intelligence

WebBioBank™ captures every moment of therapy in a secure, longitudinal cloud repository — turning continuous neural data into actionable insight for clinicians and researchers.

Neural Sensing

IPG continuously records LFPs and therapy parameters every 10 minutes, 24/7, from every electrode

Wireless

At-Home Upload

Patient remote collects and transmits data automatically each time the device is recharged, no clinic needed

WebBioBank™ Cloud

Secure longitudinal repository stores structured neural, therapy, and outcome data across all patients and sites

AI analysis

Clinical Intelligence

Clinician dashboards, biomarker reports, population trends, and AI-driven therapy optimization insights

Encrypted

Continuous Refinement

Remotely captured data across all patient populations allows for rapid trend analysis. Therapy optimization is directly pushed back to a patient’s system.